If you must take holidays during the season, try to take them when there are no matches on!
There is a Saturday off on the 18th July, and the following week (25/7) is the cup quarter finals. So for some teams, you will have no matches for 2 weekends in a row.
So before you take a holiday in June or August and miss 3 matches, think about the period from Sunday 12th until Friday 31st July.
Other cup dates that may become free: May 9, June 6, Aug 22 & Sep 25. The league ends on September 18.